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Active contour Arteriolar-to-venular ratio artery/vein classification bifurcation Blood vessels computer-aided diagnosis Diabetes diabetic retinopathy DRS fovea fractal dimension Fundus images graph Image segmentation MMSE Noise Reduction ophthalmologic images optic disc Optic disc detection Orientation scores Retina RetinaCAD RetinaCheck Retinal image Retinal image analysis retinal images speech processing vessel biomarkers Vessel segmentation Vessel width