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Arteriolar-to-venular ratio artery/vein classification bifurcation computer-aided diagnosis Dereverberation Diabetes diabetic retinopathy DRS Feature extraction fractal dimension Fundus images graph Image segmentation MMSE Noise Reduction ophthalmologic images optic disc Optic disc detection Orientation scores Retina RetinaCAD Retinal image Retinal image analysis retinal images Retinal Vascular Changes Retinal vessel segmentation speech processing vessel biomarkers Vessel segmentation Vessel width